KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP7
All Species:
31.21
Human Site:
S525
Identified Species:
49.05
UniProt:
Q93009
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93009
NP_003461.2
1102
128302
S525
Y
I
R
E
S
K
L
S
E
V
L
Q
A
V
T
Chimpanzee
Pan troglodytes
XP_510806
1102
128297
S525
Y
I
R
E
S
K
L
S
E
V
L
Q
A
V
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536979
1086
126326
S509
Y
I
R
E
S
K
L
S
E
V
L
Q
A
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4J8
1103
128457
S526
Y
I
R
E
S
K
L
S
E
V
L
Q
A
V
T
Rat
Rattus norvegicus
Q4VSI4
1103
128413
S526
Y
I
R
E
S
K
L
S
E
V
L
Q
A
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506396
1145
132881
S568
Y
I
R
E
S
K
L
S
E
V
L
Q
A
V
T
Chicken
Gallus gallus
Q6U7I1
1101
128279
S525
Y
I
R
E
S
K
L
S
E
V
L
Q
P
V
T
Frog
Xenopus laevis
NP_001121282
534
61718
V42
P
R
I
P
P
N
P
V
I
N
G
N
V
A
M
Zebra Danio
Brachydanio rerio
XP_691215
1103
128646
S526
Y
I
R
E
S
K
L
S
E
V
L
Q
P
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYQ8
1129
130428
D552
Y
I
R
Q
S
E
L
D
R
V
L
G
D
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q7JKC3
1135
131579
P512
A
I
D
Q
F
L
A
P
I
P
D
S
Q
I
P
Sea Urchin
Strong. purpuratus
XP_780569
1189
136707
N620
Y
I
R
D
S
C
M
N
E
V
V
M
K
D
V
Poplar Tree
Populus trichocarpa
XP_002316470
1116
130731
E525
Y
I
R
E
S
D
K
E
K
V
I
C
N
V
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WU2
1115
130630
D526
Y
I
R
E
S
D
K
D
K
I
I
C
N
V
D
Baker's Yeast
Sacchar. cerevisiae
P50101
1230
143545
E540
Y
I
R
Q
E
Q
E
E
D
L
L
R
P
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.7
N.A.
99
99
N.A.
92.4
95.9
46
94
N.A.
48.5
N.A.
34.4
54.5
Protein Similarity:
100
99.9
N.A.
98
N.A.
99.7
99.8
N.A.
94.7
97.9
47.4
96.8
N.A.
67.5
N.A.
52.5
69.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
93.3
0
93.3
N.A.
53.3
N.A.
6.6
40
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
93.3
0
93.3
N.A.
73.3
N.A.
20
66.6
Percent
Protein Identity:
36.9
N.A.
N.A.
36.5
29.4
N.A.
Protein Similarity:
54.3
N.A.
N.A.
54.7
47.8
N.A.
P-Site Identity:
46.6
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
0
0
0
0
0
40
7
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
14
0
0
0
% C
% Asp:
0
0
7
7
0
14
0
14
7
0
7
0
7
7
14
% D
% Glu:
0
0
0
67
7
7
7
14
60
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
94
7
0
0
0
0
0
14
7
14
0
0
14
0
% I
% Lys:
0
0
0
0
0
54
14
0
14
0
0
0
7
0
0
% K
% Leu:
0
0
0
0
0
7
60
0
0
7
67
0
0
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% M
% Asn:
0
0
0
0
0
7
0
7
0
7
0
7
14
0
0
% N
% Pro:
7
0
0
7
7
0
7
7
0
7
0
0
20
0
7
% P
% Gln:
0
0
0
20
0
7
0
0
0
0
0
54
7
0
0
% Q
% Arg:
0
7
87
0
0
0
0
0
7
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
80
0
0
54
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% T
% Val:
0
0
0
0
0
0
0
7
0
74
7
0
7
74
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
87
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _